ApalyRx
For Manufacturers

Employer Direct - Operationally Simple

Without Disrupting Your Existing Channel Strategy

ApalyRx is the operational layer for manufacturer direct-to-employer programs - configurable rules, eRx intake, real-time fulfillment routing, medical claims settlement, accumulator reporting, and decision-level documentation. Your programs run inside the benefit, not outside it.

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The Current Problem

Why Manufacturers Lose Market Share

1

Contract-Driven Access

Preferred access is determined upstream through PBM contracting and rebate economics - not clinical value. Your products compete on deal structure rather than outcomes, and your direct pricing programs sit outside the benefit where plans cannot see them.

2

Market Share Pressure

Preferred positioning shifts based on rebate renegotiations and formulary changes outside your control. Even when your product offers the best net cost, the plan has no independent way to verify that - and no infrastructure to route to you directly.

3

No Infrastructure for Direct-to-Employer

Launching a direct-to-employer program requires eRx intake, eligibility validation, cost-share collection, accumulator reporting, medical-claim billing, and supplier settlement. Most manufacturers do not have this infrastructure - and building it is not your core business.

4

Channel Considerations

Manufacturers want to serve employer demand directly but hesitate due to channel complexity and existing contractual relationships. A parallel pathway that preserves PBM relationships while opening direct access - with documented proof of program value - has not existed until now.

💸 Result: Billions invested in patient access programs that remain invisible to the benefit - and no operational infrastructure to change it.

The ApalyRx Solution

Why Manufacturers Use ApalyRx

The infrastructure you'd have to build - but don't have to

Operate at Scale

Complete End-to-End Infrastructure

90 daysto launch

ApalyRx provides the full operating layer: eRx intake, program rules and conversion logic, eligibility validation, cost-share collection, accumulator reporting, medical-claim billing, and automated supplier settlement via ACH. Your programs run like a seamless benefit - not a parallel vendor workflow.

Preserve Your PBM Channel

Parallel Pathway, Zero Disruption

0%disruption

ApalyRx operates as a parallel employer pathway alongside existing PBM contracts. Your PBM relationships stay intact. Direct-to-employer programs run through ApalyRx independently - scoped, documented, and structurally separate from PBM adjudication.

Demand Aggregation

Access Employer Lives at Scale

500K+lives today

Access 500K+ covered lives today through ApalyRx’s employer and health plan network - with growth to 1M+ by Q2 and 5M+ in pipeline. ApalyRx aggregates employer demand so you reach eligible patients through a documented benefit channel, not a fragmented cash-pay workaround.

Set Your Price

Transparent Pass-Through Economics

100%your control

You set competitive direct pricing under your commercial terms. ApalyRx passes it through transparently to the plan - no spread, no markup on drug cost. Every transaction generates a decision-level record showing why your channel was selected, giving employers documented proof of program value.

Your products. Your pricing. Inside the benefit. Fully documented.

Quick Launch

4-Step Launch Process

From product upload to market access in weeks, not months

1

Load Products & Pricing

Upload your products and set pricing under your commercial terms. Define program parameters, conversion logic, and handling requirements. Full control over your economics.

2

We Bring the Clients

ApalyRx connects your programs with employer and health plan clients. Aggregated demand, no direct sales overhead. Your programs are evaluated inside the benefit alongside all other channels.

3

We Run the Operations

Eligibility validation, program rules, PA/UM workflows, cost-share collection, accumulator reporting, medical-claim billing, and supplier settlement. Turnkey operations with decision-level documentation for every prescription.

4

Turnkey Fulfillment

Prescriptions routed to licensed independent partner pharmacies serving as pharmacy of record. Product shipped directly to the member via your designated logistics or third-party carrier. White-glove member experience with tracking and concierge support.

Enterprise Platform

Secure, Compliant, and Documented

Pricing visible only to authorized parties

Audit logs, controlled access, structured governance

HIPAA compliant, SOC 2 Type II controls

No channel disruption - parallel pathway preserving existing contracts

Decision-level records for every prescription - channels compared, rules applied, routing rationale

Fiduciary-grade documentation supporting employer ERISA and CAA audit requirements

Common Manufacturer Questions

(and how ApalyRx addresses them)

ApalyRx programs operate with defined commitment windows - typically 12 months. Volume is predictable because programs are configured with specific employer populations, drug scope, and channel rules. You have full visibility into program participation.

No. ApalyRx operates as a parallel employer pathway that is structurally separate from PBM adjudication. Your PBM contracts remain intact. Programs are scoped, documented, and do not interfere with existing formulary or rebate arrangements. Many PBMs are choosing to offer ApalyRx as part of their own program - independent routing strengthens their client relationships.

You set your own pricing under your commercial terms. ApalyRx passes it through transparently - no spread, no markup on drug cost. Pricing is visible only to authorized parties with contractual protections and structured governance.

Minimal. ApalyRx provides turnkey execution - benefit configuration, eRx intake, eligibility validation, program rules, fulfillment orchestration, cost-share collection, accumulator reporting, medical-claim billing, and supplier settlement. You supply product and define program parameters. We handle everything else - including decision-level documentation.

No. ApalyRx operates a scalable platform model. You contract with ApalyRx, and we manage the employer and health plan relationships. Your programs reach aggregated demand through a single operational integration.

ApalyRx supports configurable clinical guardrails - light-touch PA/UM workflows, conversion logic, and eligibility criteria that you and the employer define. The goal is appropriate use with minimal friction for prescribers and members.

Members receive a true benefit experience - clear costs, status tracking, concierge support, and home delivery. Prescribers use standard e-prescribing to send prescriptions to ApalyRx. No new portals, no additional steps for routine prescribing. The experience is designed to feel like a premium benefit, not a workaround.

ApalyRx provides de-identified reporting and structured data governance. The platform is HIPAA compliant with SOC 2 Type II controls. Pricing is protected, access is controlled, and audit logs document every action.

ApalyRx has been operating since 2018 and serves Fortune 500 employers. The platform is built for scale - multi-product, multi-employer, multi-program - with automated operations that do not require linear headcount growth.

ApalyRx currently covers 500K+ lives, with growth to 1M+ by Q2 and 5M+ in the pipeline across employers, health plans, and PBMs. Employer demand for manufacturer-direct programs is accelerating as plans seek transparent, lowest-net-cost alternatives with independent documentation.

In manufacturer-direct models, ApalyRx routes prescriptions to licensed independent partner pharmacies that serve as pharmacy of record. The pharmacist conducts drug utilization review and final dispense verification. Product is shipped directly to the member from your designated logistics provider or a third-party carrier. The pharmacy of record model provides the regulatory and clinical framework while your logistics handle physical fulfillment.

Drug Benefit Integrity (DBI) is an independent industry standard with five structural requirements for ensuring pharmacy benefit decisions are made in the plan’s interest. ApalyRx meets all five - including evaluating manufacturer-direct programs inside the benefit rather than leaving them invisible to the plan. For manufacturers, this means your programs are evaluated on merit alongside all other channels, and every routing decision is independently documented. When your program offers the best net cost, there is proof. Learn more at drugbenefitintegrity.com.

Launch Your Employer Direct Program

Turn-Key Infrastructure. Inside the Benefit. Fully Documented.

Tell us about your product portfolio and employer-direct objectives. We will show you how ApalyRx can operationalize your programs at scale - with transparent economics, decision-level documentation, and access to a growing network of employer and health plan clients.

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